Research Articles
Small Molecule Inhibitors for Dendritic Cell Generation from Bone Marrow: Mechanisms, Methods, and Therapeutic Applications
This comprehensive review explores the innovative use of small molecule inhibitors to generate and mature dendritic cells (DCs) from bone marrow precursors, a rapidly advancing field in cancer immunotherapy and...
Validating Immune Responses in In Vitro Skin Sensitization Models: A Guide for Researchers and Developers
This article provides a comprehensive overview of the strategies and challenges in validating immune responses for in vitro skin sensitization models.
High-Throughput Flow Cytometry Immunophenotyping of Human Blood: A Comprehensive Guide for Robust Pipeline Design and Execution
This article provides a comprehensive guide for researchers and drug development professionals on implementing high-throughput flow cytometry for deep immunophenotyping of human blood.
Achieving Cross-Lab Reproducibility in Immunological Assays: A Framework for Standardization, Validation, and Best Practices
This article provides a comprehensive framework for researchers, scientists, and drug development professionals aiming to improve the reproducibility of immunological assays across different laboratories.
AI in Immunology: Benchmarking Protein Structure Prediction Models for Antibodies, TCRs, and Vaccine Design
This article provides a comparative analysis of AI-driven protein structure prediction models, with a specialized focus on immunology applications.
Validating Multi-Organ-on-a-Chip Systems to Recapitulate Human Immunity for Next-Generation Therapeutic Development
This article explores the groundbreaking role of validated multi-organ-on-a-chip (MOC) systems in revolutionizing preclinical research by accurately modeling human immune responses.
Beyond the Dish: How 3D Culture is Reshaping Our Understanding of Macrophage Biology and Drug Discovery
This article provides a comprehensive comparison between traditional 2D and advanced 3D culture systems for macrophages, crucial innate immune cells.
A Comprehensive Guide to In Vitro Immunogenicity Assessment for Peptide-Based Vaccines
This article provides a systematic framework for researchers and drug development professionals to evaluate the immunogenicity of peptide-based vaccines using in vitro assays.
Comparative Analysis of Machine Learning Methods in Computational Immunology: From Algorithms to Clinical Translation
This article provides a comprehensive comparative analysis of machine learning (ML) methods revolutionizing computational immunology.
Benchmarking Single-Cell Annotation Methods for T Cell Subsets: A Comprehensive Guide for Immunologists and Bioinformaticians
This comprehensive review examines the current landscape of computational methods for annotating T cell subsets in single-cell RNA sequencing data.